GLP-1R/CRE Luciferase Reporter HEK293 Cell Line

供应商：BPS Bioscience

细胞类型：稳转细胞系

品系：HEK293

组织来源：/

相关疾病：多种

物种来源：human

免疫类型：多种

器官来源：无

运输方式：干冰

年限：10

生长状态：良好

CAS号：无

英文名：GLP-1R/CRE Luciferase Reporter HEK293 Cell Line

注册证号：/

规格:2管

Recombinant HEK293 cells expressing firefly luciferase gene under the control of cAMP response element (CRE) with constitutive expression of human GLP-1R (Glucagon-like peptide 1 receptor; accession number BC113493).GLP-1R, a member of the class B family of G protein-coupled receptors (GPCRs) primarily found in pancreatic β cells, is activated by a peptide hormone, glucagon-like peptide 1 (GLP-1) that is secreted from intestinal L-cells after nutrient ingestion. GLP-1R plays an important role in controlling blood sugar level by enhancing glucose-stimulated insulin secretion, so various research efforts have focused on the regulation of the GLP-1R mediated signaling pathway as a therapeutic approach to diabetes.

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